In order to effectively detect the defects for fabric image with complex texture, this paper proposed a novel detection algorithm based on an end-to-end convolutional neural network. First, the proposal regions are generated by RPN (regional proposal Network). Then, Fast Region-based Convolutional Network method (Fast R-CNN) is adopted to determine whether the proposal regions extracted by RPN is a defect or not. Finally, Soft-NMS (non-maximum suppression) and data augmentation strategies are utilized to improve the detection precision. Experimental results demonstrate that the proposed method can locate the fabric defect region with higher accuracy compared with the state-of- art, and has better adaptability to all kinds of the fabric image.