To test the packaging integrity of high polymer micro-device fabricated by UV-LIGA technique, a new method of non-destructive testing was presented. This method is based on conductance analysis principle of electrochemistry. Dependence on the slight change of the current value in the solution, the packaging integrity of micro-device was measured and the stability of the packaging method was evaluated. The experiment apparatus for the conductance analysis method was built, and applied to test the packaging integrity of the micro-device. The experimental results show that the presented testing method is effective to measure the packaging integrity of the micro-device.
The biodegradable controlled-release system with large array of micro chambers is a new controlled drug delivery system. The structure of the system is designed using the MEMS technology, combining the drug release condition and the biodegradable characteristic of the polymer. This type of drug delivery system has some unique advantages in controlled long-term drug delivery, such as more drug loading than the matrices release systems, easier control the release rate, and so on. It is necessary to optimum the structure for the long-term drug delivery. This paper founds the simulated modeling which can simulate the erosion and the drug delivery from this controlled-release system. Further more the thickness of the chamber's wall is taken as the design variable. An optimized modeling for the drug delivery
from the biodegradable controlled-release system is developed. This model can optimize the structure of the controlled release system for the desired release characteristics. The results indicate that this method can be used to design the drug delivery system based on the biodegradable polymer.