Optical sensing of specific molecular target using near-infrared light has been recognized to be the crucial technology,
have changing human's future. The imaging of Fluorescence Molecular Tomography is the most novel technology in
optical sensing. It uses near-infrared light(600-900nm) as instrument and utilize fluorochrome as probe to take noncontact
three-dimensional imaging for live molecular targets and to exhibit molecular process in vivo. In order to solve
the problem of forward simulation in FMT, this paper mainly introduces a new simulation modeling. The modeling
utilizes Monte Carlo method and is implemented in C++ programming language. Ultimately its accuracy has been
testified by comparing with analytic solutions and MOSE from University of Iowa and Chinese Academy of Science.
The main characters of the modeling are that it can simulate both of bioluminescent imaging and FMT and take analytic
calculation and support more than one source and CCD detector simultaneously. It can generate sufficient and proper
data and pre-preparation for the study of fluorescence molecular tomography.