Cardiovascular disease is one of the major diseases that cause human death. Atherosclerotic plaque rupture is the main pathogenesis of cardiovascular disease, which leads to coronary heart disease, such as myocardial ischemia, myocardial infarction, internal carotid atherosclerosis and other cardiovascular and cerebrovascular diseases. Intravascular optical coherence tomography (IVOCT) plays an important role in the diagnosis and treatment of cardiovascular diseases because of its high speed and high resolution. In the current various imaging examination method, clinician evaluate the coronary atherosclerotic plaque structural change by using intravascular ultrasound (IVUS) and IVOCT. IVOCT can provide micron size resolution, which is ten times of IVUS. However, the collected images have motion artifacts during the catheter is pulled back due to the periodic heartbeats. The artifacts would reduce the recognition accuracy of the plaques type and affect the preoperative planning and postoperative follow-up of percutaneous coronary intervention surgery. Based on the comprehensive analysis of the mechanism of motion artifacts and the characteristics of periodic cardiac motion, we designed a new algorithm to correct the rigid motion artifacts of coronary IVOCT images that caused by the heartbeat. This new algorithm can compensate part of translation to suppress of motion artifacts. Compared with the electrocardiogram control method, this algorithm does not need to discard the useful frames in the cardiac cycle, thus ensuring the integrity of the images.
Optical coherence tomography (OCT) is a new medical imaging technology that developed at the end of the 20th century after X-ray, computed tomography (CT), magnetic resonance imaging (MRI), and intravascular ultrasound (IVUS). It is called “optical biopsy” technology with the advantages of no radiation, simple structure and high resolution that can reach ten times that of IVUS. However, OCT also has the disadvantage of insufficient depth of detection that only a few millimeters and imaging speed. Even so, OCT can be used in combination with microscopes, medical catheters and endoscopes; therefore, it has broad application prospects in the field of biomedicine. The OCT system is simple in structure, mainly Michelson interferometer. Using the principle of optical coherence imaging, it detects the back-reflecting or scattering signals of incident light at different depths of biological tissue to obtain the surface and subsurface imaging of transparent or opaque substances. The combination of OCT and endoscopy extends the use of OCT to the diagnosis of cardiovascular diseases, which is called intravascular optical coherence tomography (IVOCT). It enables rapid visualization of microscopic images of vascular cross sections and is a powerful tool for clinical detection of coronary atherosclerosis, in which coronary artery calcification is a common problem in the clinic and is closely related to cardiovascular diseases. This review will briefly introduce the principle of OCT technology and its application in cardiovascular diseases, and focus on the research progress of detection of coronary artery calcification based on OCT technology.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.