Point spread functions (PSF) of a given OCT system in both longitudinal and transversal directions often cause bluring in
OCT images. A two-dimensional sharpening method is proposed to simultaneously deconvolve both the longitudinal and
transversal PSFs. This is achieved through employing an artificial kernel formed by a two-dimensional matrix,
incoroporating the product of the longitudinal and transversal PSFs. For comparison, both Wiener and Lucy-Richardson
algorithms are used for the two dimensional deconvolution. The experimental results show that these two deconvolution
algorithms can enhance the image sharpness effectively in both longitudinal and transversal directions.