Produce orthopedics surgical guides with the assistance of computer-aided design and three-dimensional (3D) printing techniques, to provide supports for doctors before or during surgeries. We develop a software which was programmed by C/C++ language, using the development tool MFC for interface and OpenGL for graphics processing. The software was used to personalized orthopedics surgical guides, and the finite element analysis of the orthopedics surgical guide was carried out. And then the solid model of the orthopedics surgical guide was printed through 3D printer. The finite element analysis of the 3D model shows that the model can meet the requirements in accuracy and stability and the final generated model of the orthopedics surgical guide can closely fit the spine bone model.