Dr. Yuanlong Yang Profile

Dr. Yuanlong Yang

at City College of New York

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Author

Publications (23)

Proceedings Article | 19 March 2013 Paper

The efficacy of Stokes Shift Spectroscopy for detecting prostate and breast cancer tissues

Yang Pu, W. Wang, Yuanlong Yang, Robert Alfano

Proc. SPIE. 8577, Optical Biopsy XI

KEYWORDS: Breast, Cancer, Breast cancer, Tissues, Spectroscopy, Luminescence, Collagen, Solids, Prostate, Absorption

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SPIE Journal Paper | 7 January 2013

Stokes shift spectroscopic analysis of multifluorophores for human cancer detection in breast and prostate tissues

Yang Pu, Wubao Wang, Yuanlong Yang, Robert Alfano

JBO Vol. 18 Issue 01

KEYWORDS: Tissues, Collagen, Breast, Cancer, Spectroscopy, Prostate, Breast cancer, Solids, Biological research, Luminescence

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SPIE Journal Paper | 10 October 2012

Biomarkers spectral subspace for cancer detection

Yi Sun, Yang Pu, Yuanlong Yang, Robert Alfano

JBO Vol. 17 Issue 10

KEYWORDS: Cancer, Tissues, Collagen, Principal component analysis, Luminescence, Signal detection, Breast cancer, Breast, Fluorescence spectroscopy, Biological research

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Proceedings Article | 1 February 2012 Paper

Optical spectroscopic characteristics of lactate and mitochondrion as new biomarkers in cancer diagnosis: understanding Warburg effect

C.-H. Liu, X. H. Ni, Yang Pu, Y. L. Yang, F. Zhou, R. Zuzolo, W. B. Wang, V. Masilamani, A. Rizwan, R. Alfano

Proc. SPIE. 8220, Optical Biopsy X

KEYWORDS: Breast, Cancer, Tissues, Spectroscopy, Luminescence, Raman spectroscopy, Optical spectroscopy, Acquisition tracking and pointing, Tissue optics, Mode conditioning cables

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Proceedings Article | 17 February 2011 Paper

Dynamics of hybrid amoeba proteus containing zoochlorellae studied using fluorescence spectroscopy

C.-H. Liu, B. A. Fong, S. A. Alfano, I. Rakhlin, W. B. Wang, X. H. Ni, Y. L. Yang, F. Zhou, R. C. Zuzolo, R. R. Alfano

Proc. SPIE. 7895, Optical Biopsy IX

KEYWORDS: Proteins, Tumor growth modeling, Cancer, Spectroscopy, Luminescence, Composites, Fluorescence spectroscopy, Organisms, Chromophores, Photosynthesis

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The microinjection of organelles, plants, particles or chemical solutions into Amoeba proteus coupled with spectroscopic analysis and observed for a period of time provides a unique new model for cancer treatment and studies. The amoeba is a eukaryote having many similar features of mammalian cells. The amoeba biochemical functions monitored spectroscopically can provide time sequence in vivo information about many metabolic transitions and metabolic exchanges between cellar organelles and substances microinjected into the amoeba. It is possible to microinject algae, plant mitochondria, drugs or carcinogenic solutions followed by recording the native fluorescence spectra of these composites. This model can be used to spectroscopically monitor the pre-metabolic transitions in developing diseased cells such as a cancer. Knowing specific metabolic transitions could offer solutions to inhibit cancer or reverse it as well as many other diseases. In the present study a simple experiment was designed to test the feasibility of this unique new model by injecting algae and chloroplasts into amoeba. The nonradiative dynamics found from these composites are evidence in terms of the emission ratios between the intensities at 337nm and 419nm; and 684nm bands. There were reductions in the metabolic and photosynthetic processes in amoebae that were microinjected with chloroplasts and zoochlorellae as well of those amoebae that ingested the algae and chloroplasts. The changes in the intensity of the emissions of the peaks indicate that the zoochlorellae lived in the amoebae for ten days. Spectral changes in intensity under the UV and 633nm wavelength excitation are from the energy transfer of DNA and RNA, protein-bound chromophores and chlorophylls present in zoochlorellae undergoing photosynthesis. The fluorescence spectroscopic probes established the biochemical interplay between the cell organelles and the algae present in the cell cytoplasm. This hybrid state is indicative that a symbiotic system is in place and the results definitely support the potential use of this unique new model. This model many help in plant / animal and cancer processes.

Proceedings Article | 8 September 2006 Paper

Time-frequency analysis of classical and quantum noise

Y. Yang, L. Cohen

Proc. SPIE. 6313, Advanced Signal Processing Algorithms, Architectures, and Implementations XVI

KEYWORDS: Oscillators, Signal processing, Time-frequency analysis

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Proceedings Article | 13 July 2004 Paper

Stokes shift emission spectroscopy of key biomolecules in human tissues

Robert Alfano, Yuanlong Yang

Proc. SPIE. 5326, Optical Biopsy V

KEYWORDS: Breast, Cancer, Breast cancer, Tissues, Spectroscopy, Luminescence, Molecules, Fluorescence spectroscopy, Collagen, Absorption

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Proceedings Article | 4 July 2000 Paper

DNA and protein change in human breast tissues by diffuse reflectance spectrum

Yuanlong Yang, Edward Celmer, Jason Koutcher, Peng Ho, Robert Alfano

Proc. SPIE. 4082, Optical Sensing, Imaging, and Manipulation for Biological and Biomedical Applications

KEYWORDS: Breast, Proteins, Cancer, Diffuse reflectance spectroscopy, Tissues, Scattering, Pathology, Luminescence, Holmium, Absorption

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Proceedings Article | 19 April 2000 Paper

DNA and protein change in tissues probed by Kubelka-Munk spectral function

Yuanlong Yang, Edward Celmer, Jason Koutcher, Robert Alfano

Proc. SPIE. 3917, Optical Biopsy III

KEYWORDS: Breast, Proteins, Cancer, Diffuse reflectance spectroscopy, Tissues, Scattering, Pathology, Spectroscopy, Light scattering, Absorption

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Proceedings Article | 19 April 2000 Paper

Ultraviolent and blue 2D fluorescence mapping of gynecological tissues

Alvin Katz, Howard Savage, Yuanlong Yang, Fanan Zeng, Jayson Rome, Steven McCormick, Rubina Cocker, Yizhong Yu, Robert Alfano

Proc. SPIE. 3917, Optical Biopsy III

KEYWORDS: Cancer, Tumors, Tissues, Pathology, Ultraviolet radiation, Luminescence, Image analysis, Collagen, Shape analysis, Cervical cancer

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Proceedings Article | 15 July 1999 Paper

Excitation spectroscopy reveals changes of proteins and the degree of invasion in malignant tissues

Yuanlong Yang, Edward Celmer, Jason Koutcher, Robert Alfano

Proc. SPIE. 3597, Optical Tomography and Spectroscopy of Tissue III

KEYWORDS: Breast, Proteins, Cancer, Tumors, Tissues, Pathology, Spectroscopy, Collagen, Colon, Ultrafast laser spectroscopy

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Proceedings Article | 16 April 1998 Paper

Optical fluorescence and Raman biopsy of squamous cell carcinoma from the head and neck

Yuanlong Yang, C. Liu, Howard Savage, Stimson Schantz, Robert Alfano

Proc. SPIE. 3250, Optical Biopsy II

KEYWORDS: Neck, Tumors, Tissues, Spectroscopy, Luminescence, Diagnostics, Raman spectroscopy, Biopsy, Head, Lymphatic system

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Proceedings Article | 18 August 1997 Paper

Biochemical distinctions between normal and cancerous human breast tissues obtained from fluorescence spectroscopy

Niclolay Zhadin, Yuanlong Yang, Nathan Ockman, Robert Alfano

Proc. SPIE. 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II

KEYWORDS: Breast, Diffuse reflectance spectroscopy, Tumors, Tissues, Scattering, Ultraviolet radiation, Luminescence, Photons, Fluorescence spectroscopy, Absorption

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SPIE Journal Paper | 2 January 1997

Fluorescence spectroscopy of dermal wounds in rats

Yuanlong Yang, Lee Mitchell, Robert Alfano

JBO Vol. 2 Issue 01

KEYWORDS: Skin, Blood, Plasma, Luminescence, Fluorescence spectroscopy, Wound healing, Optical spectroscopy, Tissues, Beam splitters, Photomultipliers

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Proceedings Article | 5 April 1996 Paper

Enhancement of the fluorescence cancer diagnostic method of tissues using diffuse reflectance and the analysis of oxygenation state

Niclolay Zhadin, Yuanlong Yang, Singaravelu Ganesan, Nathan Ockman, Robert Alfano

Proc. SPIE. 2679, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases III: Optical Biopsy

KEYWORDS: Breast, Cancer, Diffuse reflectance spectroscopy, Tumors, Tissues, Blood, Luminescence, Diagnostics, Oxygen, Absorption

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Proceedings Article | 5 April 1996 Paper

Optical biopsy fiber-based fluorescence spectroscopy instrumentation

Alvin Katz, Singaravelu Ganesan, Yuanlong Yang, Gui Tang, Yury Budansky, Edward Celmer, Howard Savage, Stimson Schantz, Robert Alfano

Proc. SPIE. 2679, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases III: Optical Biopsy

KEYWORDS: Breast, Tumors, Tissues, Ultraviolet radiation, Luminescence, Fluorescence spectroscopy, Diagnostics, Biopsy, In vivo imaging, Tissue optics

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Proceedings Article | 5 April 1996 Paper

Optical spectroscopy of benign and malignant breast tissues

Yuanlong Yang, Alvin Katz, Edward Celmer, Margaret Zurawska-Szczepaniak, Robert Alfano

Proc. SPIE. 2679, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases III: Optical Biopsy

KEYWORDS: Breast, Tissues, Pathology, Spectroscopy, Luminescence, Fluorescence spectroscopy, Reflectivity, Diagnostics, Optical spectroscopy, Ultrafast laser spectroscopy

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Proceedings Article | 12 April 1995 Paper

Fluorescence spectroscopy to evaluate dermal wounds

Yuanlong Yang, Lee Mitchell, Robert Alfano

Proc. SPIE. 2387, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II

KEYWORDS: Wound healing, Biomedical optics, Spectroscopy, Skin, Luminescence, Fluorescence spectroscopy, Tissue optics, Chlorine, Spectrophotometry, Ultrafast laser spectroscopy

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Proceedings Article | 12 April 1995 Paper

Spectroscopic properties of tryptophan and bacteria

Gui Tang, Yuanlong Yang, Zuo-Zhu Huang, W. Hua, F. Zhou, S. Cosloy, Robert Alfano

Proc. SPIE. 2387, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II

KEYWORDS: Proteins, Spectroscopy, Ultraviolet radiation, Luminescence, Molecules, Fluorescence spectroscopy, Physics, Biology, Information operations, Bacteria

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Proceedings Article | 19 May 1994 Paper

Optical spectroscopy methods to detect colon cancer

Yuanlong Yang, Gui Tang, Marc Bessler, Robert Alfano

Proc. SPIE. 2135, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases

KEYWORDS: Cancer, Tissues, Luminescence, Lamps, Optical spectroscopy, Colorectal cancer, Colon, Laser optics, Ultrafast laser spectroscopy, In vitro testing

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Proceedings Article | 5 March 1993 Paper

Microspectrophotometry of photosensitizer in single living cell of squamous epithelium carcinoma of human tongue

Yuanlong Yang, Cheng-zhi Jin, Yimin Shen Shen, Paozhong Mao, Yong Xu, Guoyu Zhou

Proc. SPIE. 1616, International Conference on Photodynamic Therapy and Laser Medicine

KEYWORDS: Microscopes, Medicine, Digital image processing, Image processing, Luminescence, Image analysis, Tongue, Digital imaging, Spectrophotometry, Absorption

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Proceedings Article | 28 October 1992 Paper

Single laser beam trapping and manipulation of microspheres as a model for biological cells

Zhong Chen, Lei Zhu, Shenyi Wang, Yuanlong Yang

Proc. SPIE. 1726, 1992 Shanghai International Symposium on Quantum Optics

KEYWORDS: Microscopes, Refractive index, Optical trapping, Optical spheres, Water, Dielectrics, Physics, Optical tweezers, Quantum optics, Geometrical optics

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Proceedings Article | 1 June 1992 Paper

Photodynamic therapy in interplay with fluorescence diagnostics in the treatment of human superficial malignancies

Torsten Andersson, Roger Berg, Jonas Johansson, Dick Killander, Katarina Svanberg, Sune Svanberg, Yuanlong Yang

Proc. SPIE. 1645, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy

KEYWORDS: Photodynamic therapy, Tumor growth modeling, Breast cancer, Tumors, Tissues, Skin, Luminescence, Dye lasers, Diagnostics, Laser induced fluorescence

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Showing 5 of 23 publications

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