Photoacoustic tomography (PAT) is a hybrid imaging method, which combines ultrasonic and optical imaging modalities, in order to overcome their respective weaknesses and to combine their strengths. It is based on the reconstruction of optical absorption properties of the tissue from the measurements of a photoacoustically generated pressure field. Current methods consider laser excitation, under thermal and stress confinement assumptions, which leads to the generation of a propagating pressure field. Conventional reconstruction tech niques then recover the initial pressure field based on the boundary measurements by iterative reconstruction algorithms in time- or Fourier-domain. Here, we propose an application of a new sensing principle that allows for efficient and non-iterative reconstruction algorithm for imaging point absorbers in PAT. We consider a closed volume surrounded by a measurement surface in an acoustically homogeneous medium and we aim at recovering the positions and the amount of heat absorbed by these absorbers. We propose a two-step algorithm based on proper choice of so-called sensing functions. Specifically, in the first step, we extract the projected positions on the complex plane and the weights by a sensing function that is well-localized on the same plane. In the second step, we recover the remaining z-location by choosing a proper set of plane waves. We show that the proposed families of sensing functions are sufficient to recover the parameters of the unknown sources without any discretization of the domain. We extend the method for sources that have joint-sparsity; i.e., the absorbers have the same positions for different frequencies. We evaluate the performance of the proposed algorithm using simulated and noisy sensor data and we demonstrate the improvement obtained by exploiting joint sparsity.
Analytic sensing has recently been proposed for source localization from boundary measurements using a generalization
of the finite-rate-of-innovation framework. The method is tailored to the quasi-static electromagnetic
approximation, which is commonly used in electroencephalography. In this work, we extend analytic sensing
for physical systems that are governed by the wave equation; i.e., the sources emit signals that travel as waves
through the volume and that are measured at the boundary over time. This source localization problem is highly
ill-posed (i.e., the unicity of the source distribution is not guaranteed) and additional assumptions about the
sources are needed. We assume that the sources can be described with finite number of parameters, particularly,
we consider point sources that are characterized by their position and strength. This assumption makes
the solution unique and turns the problem into parametric estimation. Following the framework of analytic
sensing, we propose a two-step method. In the first step, we extend the reciprocity gap functional concept to
wave-equation based test functions; i.e., well-chosen test functions can relate the boundary measurements to
generalized measure that contain volumetric information about the sources within the domain. In the second
step-again due to the choice of the test functions - we can apply the finite-rate-of-innovation principle; i.e., the
generalized samples can be annihilated by a known filter, thus turning the non-linear source localization problem
into an equivalent root-finding one. We demonstrate the feasibility of our technique for a 3-D spherical geometry.
The performance of the reconstruction algorithm is evaluated in the presence of noise and compared with the
theoretical limit given by Cramer-Rao lower bounds.
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