Dr. Zhuolin Liu Profile

Dr. Zhuolin Liu

at US Food and Drug administration

SPIE Involvement:

Conference Program Committee | Author

Publications (22)

Proceedings Article | 13 March 2024 Presentation

Full thickness retinal AO-OCT imaging with computational aberration correction

Dawid Borycki, Liu Zhuolin, Daniel Hammer, Maciej Wojtkowski

Proceedings Volume PC12824, PC128240Z (2024) https://doi.org/10.1117/12.3003993

KEYWORDS: Adaptive optics optical coherence tomography, Aberration correction, Retinal scanning, Retina, Optical components, Adaptive optics, Wavefronts, Wavefront sensors, Wavefront aberrations, Pigments

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Proceedings Article | 13 March 2024 Presentation

Reproducible retinal blood flow measurement using multimodal adaptive optics

Achyut Raghavendra, Aashka Damani, Saige Oechsli, Zhuolin Liu, Daniel Hammer, Osamah Saeedi

Proceedings Volume PC12824, PC1282406 (2024) https://doi.org/10.1117/12.3004503

KEYWORDS: Reproducibility, Blood circulation, Adaptive optics, Retinal diseases, Glaucoma, Vascular diseases, Velocity measurements, Temporal resolution, Signal to noise ratio, Scanning laser ophthalmoscopy

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Proceedings Article | 13 March 2024 Presentation

Artificial intelligence improves pixel resolution of cones from sparsely sampled AOOCT

Vineeta Das, Andrew Bower, Nancy Aguilera, Joanne Li, Zhuolin Liu, Daniel Hammer, Alfredo Dubra, Johnny Tam

Proceedings Volume PC12824, PC1282410 (2024) https://doi.org/10.1117/12.3000362

KEYWORDS: Cones, Pixel resolution, Artificial intelligence, Visualization, Transformers, Retina, Resolution enhancement technologies, Network architectures, Modeling, In vivo imaging

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Proceedings Article | 17 March 2023 Presentation

Quantitative retinal blood flow measurement in humans using adaptive optics scanning laser ophthalmoscopy and erythrocyte mediated angiography

Achyut Raghavendra, Victoria Chen, Zhuolin Liu, Daniel Hammer, Osamah Saeedi

Proceedings Volume PC12360, PC1236005 (2023) https://doi.org/10.1117/12.2651973

KEYWORDS: Blood circulation, Angiography, Adaptive optics, Scanning laser ophthalmoscopy, Line scan image sensors, Retina, Optical coherence tomography, Optic nerve, Hyperoxia, Human subjects

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Proceedings Article | 17 March 2023 Presentation

Structural metrics of the photoreceptor–pigment epithelium–choriocapillaris complex measured with 3.4 MHz adaptive optics–optical coherence tomography

Daniel Hammer, Oliver Wolcott, Achyut Raghavendra, Zhuolin Liu, Samira Aghayee, Osamah Saeedi, Catherine Cukras

Proceedings Volume PC12360, PC123600G (2023) https://doi.org/10.1117/12.2650566

KEYWORDS: Adaptive optics, Tomography, Macula, Rods, Retina, Optical coherence tomography, Image segmentation, Cones, Capillaries, Adaptive optics optical coherence tomography

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Proceedings Article | 15 March 2023 Presentation + Paper

Deep learning enables visualization of individual RPE cells from a single AO-OCT volume

Vineeta Das, Furu Zhang, Andrew Bower, Bruno Alvisio, Zhuolin Liu, Daniel Hammer, Johnny Tam

Proceedings Volume 12360, 1236004 (2023) https://doi.org/10.1117/12.2647721

KEYWORDS: Adaptive optics optical coherence tomography, Gallium nitride, Visualization, Speckle, Education and training, Deep learning, Spectral density, Image quality, Adaptive optics, Tunable filters

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Proceedings Article | 6 March 2023 Presentation

Compact linear flow phantom model for retinal blood flow evaluation

Achyut Raghavendra, Anant Agrawal, Zhuolin Liu, Daniel Hammer, Osamah Saeedi

Proceedings Volume PC12370, PC123700K (2023) https://doi.org/10.1117/12.2651971

KEYWORDS: Blood circulation, Eye models, Calibration, Systems modeling, Line scan image sensors, Angiography, Scanning laser ophthalmoscopy, Optical coherence tomography, Laser speckle imaging, Laser development

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Proceedings Article | 7 March 2022 Presentation

Adaptive optics: optical coherence tomography imaging of the inner retina in multiple sclerosis

Daniel Hammer, Zhuolin Liu, Katherine Kovalick, Osamah Saeedi, Daniel Harrison

Proceedings Volume PC11941, PC1194106 (2022) https://doi.org/10.1117/12.2608765

KEYWORDS: Coherence imaging, Retina, Optical coherence tomography, Adaptive optics, Optical imaging, Tissue optics, Pathology, Adaptive optics optical coherence tomography, Optic nerve, Nerve

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Proceedings Article | 4 March 2022 Presentation + Paper

Multifunctional and multimodal Fourier domain mode-locked laser-based adaptive optics system for ultrahigh speed retinal cellular imaging

Zhuolin Liu, Furu Zhang, Kelvy Zucca, Daniel Hammer

Proceedings Volume 11941, 1194105 (2022) https://doi.org/10.1117/12.2608784

KEYWORDS: Adaptive optics, Imaging systems, Cones, Adaptive optics optical coherence tomography, Optical coherence tomography, Retinal scanning, Retina, Eye, Optical design, Scanning laser ophthalmoscopy

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Proceedings Article | 5 March 2021 Presentation

Towards in vivo imaging of ganglion cell layer somas using widely-available clinical OCT devices

Furu Zhang, Catherine Cukras, Daniel Hammer, Zhuolin Liu

Proceedings Volume 11623, 116230Y (2021) https://doi.org/10.1117/12.2582785

KEYWORDS: Optical coherence tomography, In vivo imaging, Adaptive optics, Adaptive optics optical coherence tomography, Retinal scanning, Image quality, Human vision and color perception, Clinical trials

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Proceedings Article | 5 March 2021 Presentation

Correlation between retinal ganglion layer soma and vascular densities measured with adaptive optics: optical coherence tomography

Ricardo Villanueva, Zhuolin Liu, Furu Zhang, Daniel Hammer, Osamah Saeedi

Proceedings Volume 11623, 116230K (2021) https://doi.org/10.1117/12.2583198

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Proceedings Article | 5 March 2021 Presentation

Tracking inner retinal changes associated with glaucoma progression with AO-OCT

Zhuolin Liu

Proceedings Volume 11623, 116230X (2021) https://doi.org/10.1117/12.2582639

KEYWORDS: Adaptive optics optical coherence tomography, Tissues, Optical coherence tomography, In vivo imaging, Human subjects, Axons

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Proceedings Article | 9 March 2020 Presentation

Microglia distribution and motility in human eyes measured with adaptive optics – optical coherence tomography (AO-OCT) (Conference Presentation)

Daniel Hammer, Ricardo Villanueva, Anant Agrawal, Osamah Saeedi, Zhuolin Liu

Proceedings Volume 11218, 1121818 (2020) https://doi.org/10.1117/12.2548639

KEYWORDS: Adaptive optics, Optical coherence tomography, Adaptive optics optical coherence tomography, Optical testing, Macula, Nervous system, Injuries, Retina

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Proceedings Article | 19 February 2020 Paper

Fully automatic quantification of individual ganglion cells from AO-OCT volumes via weakly supervised learning

Somayyeh Soltanian-Zadeh, Kazuhiro Kurokawa, Zhuolin Liu, Daniel Hammer, Donald Miller, Sina Farsiu

Proceedings Volume 11218, 112180Q (2020) https://doi.org/10.1117/12.2543964

KEYWORDS: Adaptive optics optical coherence tomography, Image segmentation, Optical coherence tomography, Retina, Machine learning, Adaptive optics, In vivo imaging

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Proceedings Article | 14 March 2018 Presentation

Investigation of microscopic retina with multimodal adaptive optics (Conference Presentation)

Zhuolin Liu, Anant Agrawal, Lawrence Kagemann, Johnny Tam, Daniel Hammer

Proceedings Volume 10474, 104740J (2018) https://doi.org/10.1117/12.2291689

KEYWORDS: Adaptive optics, Image segmentation, Retina, Cones, Scanning laser ophthalmoscopy, Optical coherence tomography, Image quality, Adaptive optics optical coherence tomography, Neurons, Optical design

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Proceedings Article | 8 March 2018 Paper

3D printed phantoms of retinal photoreceptor cells for evaluating adaptive optics imaging modalities

Nikita Kedia, Zhuolin Liu, Ryan Sochol, Daniel Hammer, Anant Agrawal

Proceedings Volume 10474, 104740D (2018) https://doi.org/10.1117/12.2291759

KEYWORDS: Adaptive optics, Imaging systems, Adaptive optics optical coherence tomography, Scanning laser ophthalmoscopy, 3D modeling, Eye models, Eye, Optical coherence tomography, Cones, Optical phantoms, Additive manufacturing, Two photon polymerization, 3D printing

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Proceedings Article | 19 February 2018 Paper

Method to investigate temporal dynamics of ganglion and other retinal cells in the living human eye

Kazuhiro Kurokawa, Zhuolin Liu, James Crowell, Furu Zhang, Donald Miller

Proceedings Volume 10474, 104740W (2018) https://doi.org/10.1117/12.2292413

KEYWORDS: Adaptive optics optical coherence tomography, Retina, Speckle, Neurons, Dynamic light scattering, Glia

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Proceedings Article | 28 February 2017 Paper

Tracking dynamics of photoreceptor disc shedding with adaptive optics-optical coherence tomography

Furu Zhang, Zhuolin Liu, Kazuhiro Kurokawa, Donald Miller

Proceedings Volume 10045, 1004517 (2017) https://doi.org/10.1117/12.2256146

KEYWORDS: Cones, Retina, Adaptive optics, Adaptive optics optical coherence tomography, Animal model studies, Optical coherence tomography, Eye, Video, Tomography

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Proceedings Article | 8 February 2017 Paper

Characterizing motility dynamics in human RPE cells

Zhuolin Liu, Kazuhiro Kurokawa, Furu Zhang, Donald Miller

Proceedings Volume 10045, 1004515 (2017) https://doi.org/10.1117/12.2256144

KEYWORDS: Adaptive optics, Retina, Adaptive optics optical coherence tomography, Speckle, Optical coherence tomography, Correlation function, In vivo imaging, Eye, Tomography, Physiology, Axons, Video, Image segmentation, Imaging systems

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Proceedings Article | 4 March 2016 Presentation + Paper

Imaging human retinal pigment epithelium cells using adaptive optics optical coherence tomography

Zhuolin Liu, Omer Kocaoglu, Timothy Turner, Donald Miller

Proceedings Volume 9693, 96931E (2016) https://doi.org/10.1117/12.2212753

KEYWORDS: Adaptive optics, Adaptive optics optical coherence tomography, Optical coherence tomography, In vivo imaging, Image segmentation, Algorithm development, Retinal scanning, Retina, Eye, 3D image processing, Cones, Signal to noise ratio, Reflectivity, Image registration, Rods

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Proceedings Article | 20 March 2015 Paper

Imaging modal content of cone photoreceptors using adaptive optics optical coherence tomography

Zhuolin Liu, Omer Kocaoglu, Timothy Turner, Donald Miller

Proceedings Volume 9307, 930712 (2015) https://doi.org/10.1117/12.2083641

KEYWORDS: Cones, Adaptive optics optical coherence tomography, Image segmentation, Adaptive optics, Geometrical optics, Resolution enhancement technologies, Reflectivity, Optical coherence tomography, Image quality, Solids

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Proceedings Article | 9 March 2012 Paper

Adaptive optics optical coherence tomography for measuring phase and reflectance dynamics of photoreceptors

Omer Kocaoglu, Ravi Jonnal, Sangyeol Lee, Qiang Wang, Zhuolin Liu, Donald Miller

Proceedings Volume 8209, 82091I (2012) https://doi.org/10.1117/12.910530

KEYWORDS: Cones, Adaptive optics optical coherence tomography, Phase measurement, Reflectivity, Optical coherence tomography, Image resolution, Adaptive optics, Retina, Image segmentation, Eye

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Showing 5 of 22 publications

Conference Committee Involvement (4)

Ophthalmic Technologies XXXV

25 January 2025 | San Francisco, California, United States

Ophthalmic Technologies XXXIV

27 January 2024 | San Francisco, California, United States

Ophthalmic Technologies XXXIII

28 January 2023 | San Francisco, California, United States

Ophthalmic Technologies XXXII

22 January 2022 | San Francisco, California, United States

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