Diffuse optical tomography (DOT) is an emerging technique for biomedical imaging. The imaging quality of the DOT
strongly depends on the reconstruction algorithm. In this paper, four inhomogeneities with various shapes of absorption
distributions are simulated by a continues-wave DOT system. The DOT images are obtained based on the simultaneous
iterative reconstruction technique (SIRT) method. To solve the trade-off problem between time consumption of
reconstruction process and accuracy of reconstructed image, the iteration process needs a optimization criterion in
algorithm. In this paper, the comparison between the root mean square error (RMSE) and the convergence rate (CR) in
SIRT algorithm are demonstrated. From the simulation results, the CR reveals the information of global minimum in the
iteration process. Based on the CR calculation, the SIRT can offer higher efficient image reconstructing in DOT system.
Diffuse optical tomography (DOT) is a technique to assess the spatial variation in absorption and scattering properties of
the biological tissues. DOT provides the measurement of changes in concentrations of oxy-hemoglobin and deoxy-hemoglobin.
The oxygenation images are reconstructed by the measured optical signals with nearest-neighbor pairs of
sources and detectors. In our study, a portable DOT system is built with optode design on a flexible print circuit board
(FPCB). In experiments, the hemodynamics temporal evolution of exercises and vessel occlusions are observed with in
vivo measurements form normal subjects and some patients in intensive care unit.