Prof. David Mayerich
Assistant Professor at Univ of Houston
SPIE Involvement:
Profile Summary

My work focuses on high-performance computing and biomedical imaging. Maps describing tissue structure and composition are critical for understanding biological functions. This data is particularly important for research in complex phenotypes, such as the brain tissue and tumor biopsies. However, whole organ imaging is impractical with existing instrumentation and data processing algorithms. My research enables three-dimensional whole organ phenotyping by developing methods for exploring large biological samples at sub-micrometer resolution. I focus on developing new instrumentation and utilizing high-performance computing to create large-scale multi-dimensional and hyperspectral data sets that will enable advances in disease research, diagnosis, and precision medicine.
Publications (6)

Proceedings Article | 17 February 2020
Proc. SPIE. 11231, Design and Quality for Biomedical Technologies XIII
KEYWORDS: Point spread functions, Detection and tracking algorithms, Tissues, Imaging systems, Image segmentation, Ultraviolet radiation, Microscopy, Image resolution, Algorithm development, 3D image processing

Proceedings Article | 19 November 2019
Proc. SPIE. 11186, Advanced Optical Imaging Technologies II
KEYWORDS: Confocal microscopy, Deep ultraviolet, Tissues, Image segmentation, Ultraviolet radiation, Microscopy, Image resolution, Tissue optics, Natural surfaces, 3D image processing

Proceedings Article | 8 February 2017
Proc. SPIE. 10043, Diagnosis and Treatment of Diseases in the Breast and Reproductive System
KEYWORDS: Optical imaging, Coherence imaging, Refractive index, Tissues, Imaging systems, Scattering, Optical coherence tomography, Stereoscopy, Microscopy, Luminescence, Image resolution, Digital imaging, Integrated optics, Tissue optics, Illumination engineering, 3D image processing, Animal model studies

Proceedings Article | 9 March 2016
Proc. SPIE. 9716, Optical Methods in Developmental Biology IV
KEYWORDS: Optical imaging, Coherence imaging, Imaging systems, Optical coherence tomography, Microscopy, Luminescence, Image resolution, Objectives, Physiology, Spatial resolution, 3D image processing

Proceedings Article | 20 March 2014
Proc. SPIE. 9041, Medical Imaging 2014: Digital Pathology
KEYWORDS: Breast, Mid-IR, FT-IR spectroscopy, Breast cancer, Tissues, Spectroscopy, Imaging spectroscopy, Collagen, Biopsy, Infrared spectroscopy

Showing 5 of 6 publications
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