Mr. Min Jiang Profile

Min Jiang

at Nanjing Univ

SPIE Involvement:

Author

Publications (2)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 5 November 2018 Paper

Nanoparticles manipulation on plasmonic metasurface for determination of antibody in lab-on-a-chip devices

Wenhao Xu, Min Jiang, Feng Wang, Guanghui Wang, Xuping Zhang

Proceedings Volume 10814, 108140B (2018) https://doi.org/10.1117/12.2500255

KEYWORDS: Particles, Microfluidics, Nanoparticles, Polarization, Lab on a chip, Gold, Fluorescence spectroscopy, Plasmonics, Luminescence, Neon

Read Abstract +

We developed a novel lab-on-a-chip device with the capability of rapidly antibody determination that use nano-beads as the solid carriers. The device combines a plasmon-assisted optical conveyor belt in the main microfluidic channel, which is made of gold nano-ellipses perpendicular to each other. In the presence of an external uniform electric field, the hot spots in the belt function as optical tweezers can trap and transport properly sized nano-beads with target antibody combined along a fix direction through rotating the polarization. Several branch channels intersecting the main microfluidic channel at right angles are used to transport smaller antigen modified nano-beads, which can be labeled with fluorescent dyes. When arriving at the crossings, the smaller nano-beads would be trapped by hotspots on the surface of two-dimensional ellipses arrays around the conveyor belt and can’t be transported between two ellipses due to their smaller size. So, the antibody modified nano-beads would be transported along the optical conveyor belt and encounter the trapped antigen modified ones in the ellipses arrays successively. Only those ones with specific antigen combined that stick to the antibody to be measured can be dragged by bigger nano-beads and transport with it. In light of that, we can determinate the antibody by identifying the fluorescence-labelled nano-beads at the exit of the main channel. With the capacity for parallel detection, our design offers an attractive scheme for rapid, high throughput determination of antibody in microfluidic channels, which are also ease to operate.

Proceedings Article | 10 January 2018 Paper

Precise sample preconcentration based on plasmon-assisted optical manipulation for a bead-based Raman biosensor

Min Jiang, Guanghui Wang, Xuping Zhang

Proceedings Volume 10618, 106180F (2018) https://doi.org/10.1117/12.2295661

KEYWORDS: Polarization, Particles, Raman spectroscopy, Optical manipulation, Gold, Plasmonics, Lab on a chip, Nanoparticles, Biosensors, Microfluidics

Read Abstract +

We developed a novel lab-on-a-chip device with the capability of rapidly pre-concentrating for Raman detection that use gold bead as the solid carrier of biomolecules. The device combines an array of patterned plasmonic surface (i.e. gold nano-ellipses), as the bead manipulation element. The purpose of gold bead manipulation is to provide sample pre-concentration in close proximity of the Raman detecting region. In the presence of an external uniform electric field, the gold ellipses create local electric field gradients (which is usually called hot spots) that capture the gold beads. The location of hot spots within a plasmonic nanostructure is polarization dependent, and inhomogeneous electric field between two adjacent nano-ellipses perpendicular to each other leads to highly unbalanced trap potential that give the chance of transferring trapped particles in a given direction through rotating the polarization. Nano-optical conveyor belts with staircase pattern of nano-ellipses were arranged with their terminus collected at detection area to gather biomolecules. With the capacity to transfer biomolecules precisely, our design offers an attractive scheme for rapid, high throughput and highly sensitive sensing of low abundance analytes.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years