Oral cancer is a rising health issue in many low and middle income countries (LMIC). Proposed is an implementation of autofluorescence imaging (AFI) and white light imaging (WLI) on a smartphone platform providing inexpensive early detection of cancerous conditions in the oral cavity. Interchangeable modules allow both whole mouth imaging for an overview of the patients’ oral health and an intraoral imaging probe for localized information. Custom electronics synchronize image capture and external LED operation for the excitation of tissue fluorescence. A custom Android application captures images and an image processing algorithm provides likelihood estimates of cancerous conditions. Finally, all data can be uploaded to a cloud server where a convolutional neural network classifies the images and a remote specialist can provide diagnosis and triage instructions.
The Functional Freeform Fitting (F<sup>4</sup>) method is utilized to design a freeform optic for oblique illumination of Mark Rothko’s <i>Green on Blue</i> (1956). Shown are preliminary results from an iterative freeform design process; from problem definition and specification development to surface fit, ray tracing results, and optimization. This method is applicable to both point and extended sources of various geometries.
In this paper, laser modules based on newly developed tailored bars are presented. The modules allow efficient fiber coupling of more than 320 W into 10 mm-mrad or 160 W into 6 mm-mrad at one single wavelength. For further power scaling dense wavelength coupling concepts are presented which enable kW-class lasers with a beam quality of 10 mm-mrad.