Towards in-vivo non-contact measurement of the metabolic rate of oxygen in ophthalmic tissues using a dual-modal photoacoustic remote sensing and swept-source optical coherence tomography imaging system

Nima Abbasi Firoozjah; James A. Tummon Simmons; Tahereh Amiri; Zohreh Hosseinaee; Nicholas Pellegrino; Parsin Haji Reza

doi:10.1117/12.2609036

7 March 2022 Towards in-vivo non-contact measurement of the metabolic rate of oxygen in ophthalmic tissues using a dual-modal photoacoustic remote sensing and swept-source optical coherence tomography imaging system

Nima Abbasi Firoozjah, James A. Tummon Simmons, Tahereh Amiri, Zohreh Hosseinaee, Nicholas Pellegrino, Parsin Haji Reza

Author Affiliations +

Proceedings Volume PC11960, Photons Plus Ultrasound: Imaging and Sensing 2022; PC119600S (2022) https://doi.org/10.1117/12.2609036
Event: SPIE BiOS, 2022, San Francisco, California, United States

Conference Poster

Abstract

A non-contact, dual-modal imaging apparatus is introduced which will be used to obtain the Metabolic Rate of Oxygen (mRO2) in the live murine eye, based on the blood flow rate and blood Oxygen Saturation (sO2) measurements. The apparatus is comprised of both Photoacoustic Remote Sensing (PARS) and Swept-Source Optical Coherence Tomography (SS-OCT) systems, operating synchronously. A phantom model will be imaged using the proposed system to validate the accuracy of the blood flow and sO2 measurements. To the best of our knowledge, this work would report for the first time, non-contact, in-vivo measurement of the mRO2 in the ophthalmic tissues.

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Nima Abbasi Firoozjah, James A. Tummon Simmons, Tahereh Amiri, Zohreh Hosseinaee, Nicholas Pellegrino, and Parsin Haji Reza "Towards in-vivo non-contact measurement of the metabolic rate of oxygen in ophthalmic tissues using a dual-modal photoacoustic remote sensing and swept-source optical coherence tomography imaging system", Proc. SPIE PC11960, Photons Plus Ultrasound: Imaging and Sensing 2022, PC119600S (7 March 2022); https://doi.org/10.1117/12.2609036

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