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The altered placental function which is characteristic of preeclampsia is challenging to characterize with existing imaging techniques. We have developed ultrasound-guided spectral photoacoustic imaging of placental function in an in vivo rat model of preeclampsia, and investigated the impact of therapy on preeclampsia and placental function. Additionally, we have studied the acute vascular response during pregnancy – determining vascular selectivity and response time to vasoactive compounds — using photoacoustic tomography. We integrate our photoacoustic imaging methods with contrast-enhanced ultrasound to provide measures of placental vascular flow. By combining these hybrid optical-acoustic imaging techniques, we characterize placental pathologies and their responses to treatment.
Kristie Huda,Vinoin Vincely, andCarolyn L. Bayer
"Spectral photoacoustic and ultrasound imaging of vascular function", Proc. SPIE PC12363, Multiscale Imaging and Spectroscopy IV, PC123630D (17 March 2023); https://doi.org/10.1117/12.2661610
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Kristie Huda, Vinoin Vincely, Carolyn L. Bayer, "Spectral photoacoustic and ultrasound imaging of vascular function," Proc. SPIE PC12363, Multiscale Imaging and Spectroscopy IV, PC123630D (17 March 2023); https://doi.org/10.1117/12.2661610