Determining elastic contrast in tissue-mimicking phantoms using frequency resolved photoacoustic imaging

Subhamoy Mandal; Anjali Thomas; Mayanglambam Suheshkumar Singh; Dorde Komljenovic

doi:10.1117/12.2511682

27 February 2019 Determining elastic contrast in tissue-mimicking phantoms using frequency resolved photoacoustic imaging

Subhamoy Mandal, Anjali Thomas, Mayanglambam Suheshkumar Singh, Dorde Komljenovic

Author Affiliations +

Proceedings Volume 10878, Photons Plus Ultrasound: Imaging and Sensing 2019; 108782M (2019) https://doi.org/10.1117/12.2511682
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

Tissue elasticity is an important biomarker for early prediction of diseases, and elastography methods have been developed for several modalities. In practice, photoacoustic imaging (PAI) provides information about the optical properties of deep-seated tissue based on an ultrasonic readout. In this study, we demonstrate the use of PAI to measure tissue elasticity through high frequency acquisitions. The method was tested using tissue mimicking agar phantoms and transducers of different frequencies. The results show that elastic contrast can be recovered from PA signals only using high-frequency transducers, given significant differences of elasticity between the imaging target and background.

Citation Download Citation

Subhamoy Mandal, Anjali Thomas, Mayanglambam Suheshkumar Singh, and Dorde Komljenovic "Determining elastic contrast in tissue-mimicking phantoms using frequency resolved photoacoustic imaging ", Proc. SPIE 10878, Photons Plus Ultrasound: Imaging and Sensing 2019, 108782M (27 February 2019); https://doi.org/10.1117/12.2511682

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