Optical fibers are becoming popular in medicine and biomedical research together with optical methods such as endoscopy and sensing, optogenetics or photodynamic therapy. Typically, silica optical fibers are used because they offer very good transparency from visible to near infrared range of the electromagnetic spectrum and they are biocompatible, i.e. they are not toxic and they do not provoke a negative response from the immunity system. However, their use pose a certain risk to the body in case of a breakage of such fiber since the fragments are not easily detectable by X-ray imaging and they can move through venous system. Optical fibers based on water-soluble non-toxic materials such as phosphate glass can solve this issue.
In this work, we present a fabrication and both in-vitro and in-vivo characterization of an optical fiber made of undoped sodium phosphate glass.
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