Design and detection experiment of a portable platelet aggregation instrument

Huang Xiechen; Jiang Yun Wang; Cui Ma; Ming Yu; Hui Lin

doi:10.1117/12.2549972

20 December 2019 Design and detection experiment of a portable platelet aggregation instrument

Huang Xiechen, Jiang Yun Wang, Cui Ma, Ming Yu, Hui Lin

Proceedings Volume 11209, Eleventh International Conference on Information Optics and Photonics (CIOP 2019); 1120950 (2019) https://doi.org/10.1117/12.2549972
Event: Eleventh International Conference on Information Optics and Photonics (CIOP 2019), 2019, Xi'an, China

Abstract

This paper introduces a new portable platelet aggregation instrument based on optical transmittance measurement. The platelet-rich plasma is aggregated after adding trapping agent and leads to a transmittance enhancement. By analyzing the transmittance evolution curve, the platelet aggregation function can be obtained, which is helpful for doctors to do clinical diagnosis of thrombotic disease and make a prescription of drugs. The design of the optical module, the signal processing circuit, and the software are described in detail. After assembling the instrument, several tests of blood samples are carried out to verify its performance. The instrument is compact and easy to use, so it is potential for rapid detection or real-time monitoring.

Citation Download Citation

Huang Xiechen, Jiang Yun Wang, Cui Ma, Ming Yu, and Hui Lin "Design and detection experiment of a portable platelet aggregation instrument", Proc. SPIE 11209, Eleventh International Conference on Information Optics and Photonics (CIOP 2019), 1120950 (20 December 2019); https://doi.org/10.1117/12.2549972

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