Impulse generated by laser-irradiated nanostructures in water and its effects on cell poration

Weilu Shen; Nicole Black; Stefan Kalies; Eric Mazur

doi:10.1117/12.2579239

5 March 2021 Impulse generated by laser-irradiated nanostructures in water and its effects on cell poration

Weilu Shen, Nicole Black, Stefan Kalies, Eric Mazur

Proceedings Volume 11661, Plasmonics in Biology and Medicine XVIII; 116610C (2021) https://doi.org/10.1117/12.2579239
Event: SPIE BiOS, 2021, Online Only

Abstract

There are many ways to deliver biomolecules to cells past their cell membrane barrier, but the field of laser-activated materials have helped further the drug delivery field. When nanostructure and materials are irradiated by pulsed laser in an aqueous environment, thermoplasmonic effects and localized heating occur. There are also pressure waves being generated, with the quantity of impulse varying due to laser-parameter and surface type. We demonstrate the relationship between the magnitude of impulse, generated from gold thermoplasmonic nanostructure and bulk polymer substrates, and cargo delivery in cells.

Conference Presentation

Citation Download Citation

Weilu Shen, Nicole Black, Stefan Kalies, and Eric Mazur "Impulse generated by laser-irradiated nanostructures in water and its effects on cell poration", Proc. SPIE 11661, Plasmonics in Biology and Medicine XVIII, 116610C (5 March 2021); https://doi.org/10.1117/12.2579239

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