Numerical simulation in optical coherence tomography as a tool for development of emerging OCT-modalities

Lev A. Matveev; Alexander L. Matveyev; Alexander A. Moiseev; Alexander A. Sovetsky; Alexey A. Zykov; Grigory V. Gelikonov; Vladimir Y. Zaitsev

doi:10.1117/12.2590750

4 May 2021 Numerical simulation in optical coherence tomography as a tool for development of emerging OCT-modalities

Lev A. Matveev, Alexander L. Matveyev, Alexander A. Moiseev, Alexander A. Sovetsky, Alexey A. Zykov, Grigory V. Gelikonov, Vladimir Y. Zaitsev

Author Affiliations +

Proceedings Volume 11846, Saratov Fall Meeting 2020: Laser Physics, Photonic Technologies, and Molecular Modeling; 118460P (2021) https://doi.org/10.1117/12.2590750
Event: Saratov Fall Meeting 2020, 2020, Saratov, Russian Federation

Abstract

Numerical simulations of signal formation in optical coherence tomography (OCT) is a useful tool for understanding and evaluation of the actively developing novel modalities in OCT including, but not limited to elastography, angiography and high-resolution OCT-imaging based on digital refocusing. Numerical simulation of OCT signals allows one to simulate OCT scans using highly controllable parameters characterizing the tissue, e.g., position of the scatterers, their scattering properties, evolution of the scatterer positions (due to straining, Brownian motions or flows). In real or physical phantom experiments sufficiently fine control of these parameters is very complicated or even impossible, therefore the numerical simulations are preferable. We developed a full-wave model for simulations of OCT scans taking into account beam focusing/defocusing and motion of scatterers. This full-wave model can be used for studying OCT signal formation and its analysis in phase-sensitive OCT. Here we present an example of such a computational study of OCT-based angiography with numerical refocusing.

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Lev A. Matveev, Alexander L. Matveyev, Alexander A. Moiseev, Alexander A. Sovetsky, Alexey A. Zykov, Grigory V. Gelikonov, and Vladimir Y. Zaitsev "Numerical simulation in optical coherence tomography as a tool for development of emerging OCT-modalities", Proc. SPIE 11846, Saratov Fall Meeting 2020: Laser Physics, Photonic Technologies, and Molecular Modeling, 118460P (4 May 2021); https://doi.org/10.1117/12.2590750

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