Investigation of Radachlorin accumulation in 3T3 cells by fluorescence microscopy and holographic tomography

Anna A. Zhikhoreva; Andrey V. Belashov; Tatyana N. Belyaeva; Elena S. Kornilova; Irina V. Semenova; Oleg S. Vasyutinskii

doi:10.1117/12.2615832

7 December 2021 Investigation of Radachlorin accumulation in 3T3 cells by fluorescence microscopy and holographic tomography

Anna A. Zhikhoreva, Andrey V. Belashov, Tatyana N. Belyaeva, Elena S. Kornilova, Irina V. Semenova, Oleg S. Vasyutinskii

Author Affiliations +

Proceedings Volume 11922, Advances in Microscopic Imaging III; 119221M (2021) https://doi.org/10.1117/12.2615832
Event: European Conferences on Biomedical Optics, 2021, Online Only

Abstract

Accumulation of Radachlorin photosensitizer in 3T3 cells was evaluated using holographic tomography and fluorescence microscopy. Comparative analysis of images obtained by these techniques evidences drug accumulation in small intracellular structures located primarily in the juxtanuclear area.

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Anna A. Zhikhoreva, Andrey V. Belashov, Tatyana N. Belyaeva, Elena S. Kornilova, Irina V. Semenova, and Oleg S. Vasyutinskii "Investigation of Radachlorin accumulation in 3T3 cells by fluorescence microscopy and holographic tomography", Proc. SPIE 11922, Advances in Microscopic Imaging III, 119221M (7 December 2021); https://doi.org/10.1117/12.2615832

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