Paper
8 June 2022 Efficacy of ferromagnetic cores on the performance of TMS coils
Author Affiliations +
Abstract
Noninvasive electric stimulation-based treatments for neuropsychiatric disorders are of high interest in both research and clinical studies. Among them, transcranial magnetic stimulation (TMS) is widely accepted as a safe and effective method. Enhancing the performance of the apparatus requires stimulation of deeper brain regions which isn’t accessible with current coils due to the increased depth-spread tradeoff at deeper regions. In addition, focal rodent coils need to be developed to better understand brain stimulation mechanisms. Due to the smaller size of the rodent brain, a variety of challenges like the depth-spread tradeoff and high energy requirement arise when stimulating a functionally specific brain region. In this study, we have introduced tilted, wire-wrapped, multi-stacked coils for the purpose of enhancing brain stimulation for primates and non-primates. To improve the performance of the coils, we added different types of ferromagnetic cores to understand the efficacy of these cores on the distribution, decay rate, and the focality of the induced electric field. The analysis was performed using Finite Element Model (FEM) simulations, and the results were then verified using 3-d printed coils and experimental procedures. The performance of the coils was dependent on the relative permeability of the ferromagnetic core, demonstrating a general improvement in the focality and energy requirement of these TMS coils.
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Hedyeh Bagherzadeh, Sravani Varanasi, Jean-Paul Badjo, and Fow-Sen Choa "Efficacy of ferromagnetic cores on the performance of TMS coils", Proc. SPIE 12123, Smart Biomedical and Physiological Sensor Technology XIX, 121230B (8 June 2022); https://doi.org/10.1117/12.2618828
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KEYWORDS
Ferromagnetics

Finite element methods

Brain

Magnetism

Brain stimulation

Signal detection

Clinical research

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