An ultra-low-cost focus-tunable smartphone-based microscope

Haoran Zhang; Qizheng Dai; Hongying Wang; Xinyi Wang; Shiqing Zhao; Jianlong Yang; Aili Zhang

doi:10.1117/12.2646294

6 March 2023 An ultra-low-cost focus-tunable smartphone-based microscope

Haoran Zhang, Qizheng Dai, Hongying Wang, Xinyi Wang, Shiqing Zhao, Jianlong Yang, Aili Zhang

Proceedings Volume 12369, Optics and Biophotonics in Low-Resource Settings IX; 123690E (2023) https://doi.org/10.1117/12.2646294
Event: SPIE BiOS, 2023, San Francisco, California, United States

Conference Poster

Abstract

By taking advantage of the inherent flexibility of low-cost 3D printing materials, we achieved an optical focus tuning accuracy of ~5 micron with a novel structure design. It shrinks the mechanical displacement by a factor of ~11 through a seesaw-like component. Combing with the built-in flashlight illumination and an off-the-shelf smartphone lens, the total manufacturing cost of our smartphone-based microscope is less than 4 USD. We demonstrated the capability of this design in imaging thick biological specimens. We further applied this device in the cell culture monitoring of VX2 tumor cells because of its portability and flexibility.

Citation Download Citation

Haoran Zhang, Qizheng Dai, Hongying Wang, Xinyi Wang, Shiqing Zhao, Jianlong Yang, and Aili Zhang "An ultra-low-cost focus-tunable smartphone-based microscope", Proc. SPIE 12369, Optics and Biophotonics in Low-Resource Settings IX, 123690E (6 March 2023); https://doi.org/10.1117/12.2646294

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