Don't sleep on sampling: if you don’t catch it, you can’t see it

Daniel Carmany; Ashish Tripathi; Nicholas Manicke; Erik Emmons; Jason Guicheteau; Elizabeth Dhummakupt

doi:10.1117/12.2663938

14 June 2023 Don't sleep on sampling: if you don’t catch it, you can’t see it

Daniel Carmany, Ashish Tripathi, Nicholas Manicke, Erik Emmons, Jason Guicheteau, Elizabeth Dhummakupt

Proceedings Volume 12541, Chemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensing XXIV; 125410P (2023) https://doi.org/10.1117/12.2663938
Event: SPIE Defense + Commercial Sensing, 2023, Orlando, Florida, United States

Abstract

Transitioning a technical method from the laboratory bench to the field is a challenge. Initially, the method needs to fill a technical gap to a degree that a warfighter or first responder would find additional hardware and training worth the logistical burden. Second, the method should be robust to minor deviations and interferents. Finally, the resultant end point must be easily read, understood, and provide actionable information to the user. Accomplishing all these steps is key to demonstrating the value of scientific research to the warfighter and delivering a valuable tool. Recent efforts have been focused on developing methods for easy and robust trace analyte collection and portable sample identification. The analytes of interest include explosives, pharmaceutical based agents, and drugs of abuse. The collection method involves paper modified with pressure-sensitive adhesives, i.e. yellow sticky notes, to sample various types of solid, porous, and environmental surfaces. Threat identification is performed directly from the collection substrates by mass spectrometric instrumentation with tandem capabilities to identify TNT, RDX, and HMX. The surface limits of detection (LODs) of the method ranged from sub to low microgram range. An analysis mode was created that would display a green light/red light if a sample was negative/positive, respectively, for a threat. This provides an easy-to-read, actionable result while saving the analytical spectra for future review. Finally, this methodology was combined with portable Raman analysis to provide both primary and confirmatory identification of fentanyl in simulated samples and TNT in samples both collected and analyzed in an austere location.

Conference Presentation

Citation Download Citation

Daniel Carmany, Ashish Tripathi, Nicholas Manicke, Erik Emmons, Jason Guicheteau, and Elizabeth Dhummakupt "Don't sleep on sampling: if you don’t catch it, you can’t see it", Proc. SPIE 12541, Chemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensing XXIV, 125410P (14 June 2023); https://doi.org/10.1117/12.2663938

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available