Paper
9 August 2023 Monte Carlo modeling of photoacoustic guided technique in scattering media
Joya Arisu, Naoto Yamamura, Keiichi Nakagawa, Shu Takagi, Eiji Okada
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Abstract
The photoacoustic guided (PAG) technique can noninvasively increase light penetration and localization in deep tissue. The mechanism of the PAG technique is considered to be a pressure dependent refractive index change caused by acoustic wave that produces a virtual waveguide, but it is still a highly controversial issue. In this study, light propagation in the models with the PAG region was calculated by a Monte Carlo simulation. We assumed that the change in the refractive index or anisotropy factor of scattering in the PAG region contributes to the light guiding effect. Both the refractive index and anisotropy factor heterogeneities increase the photon density in the PAG region of the deep tissue part. The effect of localization of the photon density in the PAG region with the anisotropy factor heterogeneity is less significant compared to that with the refractive index heterogeneity.
© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Joya Arisu, Naoto Yamamura, Keiichi Nakagawa, Shu Takagi, and Eiji Okada "Monte Carlo modeling of photoacoustic guided technique in scattering media", Proc. SPIE 12628, Diffuse Optical Spectroscopy and Imaging IX, 126281Z (9 August 2023); https://doi.org/10.1117/12.2670646
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KEYWORDS
Anisotropy

Refractive index

Monte Carlo methods

Tissues

Geometrical optics

Photoacoustic spectroscopy

Photon transport

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