High quality optical coherence tomography imaging of mock cataract surgery with deep-learning-based denoising

Jonas Nienhaus; Anja Britten; Philipp Matten; Thomas Schlegl; Katharina Dettelbacher; Andreas Pollreisz; Wolfgang Drexler; Rainer A. Leitgeb; Tilman Schmoll

doi:10.1117/12.2670877

11 August 2023 High quality optical coherence tomography imaging of mock cataract surgery with deep-learning-based denoising

Jonas Nienhaus, Anja Britten, Philipp Matten, Thomas Schlegl, Katharina Dettelbacher, Andreas Pollreisz, Wolfgang Drexler, Rainer A. Leitgeb, Tilman Schmoll

Author Affiliations +

Proceedings Volume 12632, Optical Coherence Imaging Techniques and Imaging in Scattering Media V; 126321Q (2023) https://doi.org/10.1117/12.2670877
Event: European Conferences on Biomedical Optics, 2023, Munich, Germany

Abstract

Optical coherence tomography can provide visualizations of the eye both in diagnostic and surgical settings. However, noise limits the achievable image quality, especially in scenarios in which multi-frame averaging is not available. In this work, we present high-quality OCT image denoising using deep learning, only requiring unpaired volumetric capture scans for training. It is shown that, by exploiting neighboring B-scans, an artificial neural network for denoising OCT images can be trained based on a state-of-the-art approach which usually requires repeated scans from the exact same location. The effect of denoising is demonstrated for B-scans and volumetric renderings during and after mock cataract surgery on ex-vivo porcine eyes.

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Jonas Nienhaus, Anja Britten, Philipp Matten, Thomas Schlegl, Katharina Dettelbacher, Andreas Pollreisz, Wolfgang Drexler, Rainer A. Leitgeb, and Tilman Schmoll "High quality optical coherence tomography imaging of mock cataract surgery with deep-learning-based denoising", Proc. SPIE 12632, Optical Coherence Imaging Techniques and Imaging in Scattering Media V, 126321Q (11 August 2023); https://doi.org/10.1117/12.2670877

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KEYWORDS

Coherence imaging

Denoising

Optical coherence tomography

Cataracts

Surgery

Education and training

Optical imaging

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