Modeling wavelength dependence of laser tumor hyperthermic treatments

Alexander A. C. Wainwright; Khaled Madhoun; Fadi Farook; Souren Salehi; Samansa Maneshi; R. J. Dwayne Miller

doi:10.1117/12.3000396

12 March 2024 Modeling wavelength dependence of laser tumor hyperthermic treatments

Alexander A. C. Wainwright, Khaled Madhoun, Fadi Farook, Souren Salehi, Samansa Maneshi, R. J. Dwayne Miller

Proceedings Volume 12840, Optical Interactions with Tissue and Cells XXXV; 1284008 (2024) https://doi.org/10.1117/12.3000396
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Breast cancer is the world's most prevalent cancer, with roughly 1 in 16 Americans being diagnosed within their lifetime. One form of treatment for breast cancer is hyperthermal therapy, which involves heating cancer tumors to between 43-50 °C to cause apoptosis and above 50 °C for necrosis. Lasers are an effective method to raise the temperature of tumors for apoptosis and necrosis. However, to date, no study has compared the efficiency of visible, near infrared and mid infrared lasers for hyperthermal treatments. Here, we present a finite element model simulation using COMSOL Multiphysics to compare hyperthermal therapy using 500 nm, 900 nm, 3 μm and 10 μm laser sources using a fiber optic delivery system. Our results indicate that mid-infrared lasers result in shorter treatment times, while near infrared wavelengths likely result in less healthy tissue damage.

Conference Presentation

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Alexander A. C. Wainwright, Khaled Madhoun, Fadi Farook, Souren Salehi, Samansa Maneshi, and R. J. Dwayne Miller "Modeling wavelength dependence of laser tumor hyperthermic treatments", Proc. SPIE 12840, Optical Interactions with Tissue and Cells XXXV, 1284008 (12 March 2024); https://doi.org/10.1117/12.3000396

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