In-house developed ultra-sensitive laser stimulated fluorescence system for amino acid profiling

Megha Naik; Ajeetkumar Patil

doi:10.1117/12.3023460

15 February 2024 In-house developed ultra-sensitive laser stimulated fluorescence system for amino acid profiling

Megha Naik, Ajeetkumar Patil

Proceedings Volume 13069, International Conference on Optical and Photonic Engineering (icOPEN 2023); 130691E (2024) https://doi.org/10.1117/12.3023460
Event: International Conference on Optical and Photonic Engineering (icOPEN 2023), 2023, Singapore, Singapore

Abstract

The qualitative and quantitative assessment of amino acids holds immense significance in the realm of life sciences. It assumes a pivotal role in comprehending intricate biological processes and, importantly, in the early detection of potential disease developments, as amino acids serve as precursors for numerous biomarkers. Our amino acid profiling method offers remarkable versatility in this context, positioning it to scrutinize amino acid profiles in body fluids. Our study introduces an innovative approach to simultaneously detect amino acids through high-performance liquid chromatography combined with laser-stimulated fluorescence, displaying a picomolar detection limit. By harnessing the power of laser-stimulated fluorescence detection, our approach offers a novel pathway to enhance the understanding of amino acids' roles in health and disease.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Megha Naik and Ajeetkumar Patil "In-house developed ultra-sensitive laser stimulated fluorescence system for amino acid profiling", Proc. SPIE 13069, International Conference on Optical and Photonic Engineering (icOPEN 2023), 130691E (15 February 2024); https://doi.org/10.1117/12.3023460

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