Noninvasive hemoglobin oxygenation monitor and computed tomography by NIR spectrophotometry

Ichiro Oda; Yasunobu Ito; Hideo Eda; Tomomi Tamura; Michinosuke Takada; Rentaro Abumi; Katumi Nagai; Hachiro Nakagawa; Masahide Tamura

doi:10.1117/12.44199

1 May 1991 Noninvasive hemoglobin oxygenation monitor and computed tomography by NIR spectrophotometry

Ichiro Oda, Yasunobu Ito, Hideo Eda, Tomomi Tamura, Michinosuke Takada, Rentaro Abumi, Katumi Nagai, Hachiro Nakagawa, Masahide Tamura

Author Affiliations +

Proceedings Volume 1431, Time-Resolved Spectroscopy and Imaging of Tissues; (1991) https://doi.org/10.1117/12.44199
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States

Abstract

Using a near infrared (NIR) spectrophotometry, a compact instrument for monitoring the hemoglobin (Hb) oxygenation state in human brain was developed. Brian oxygen metabolism was non-invasively studied by simultaneous measurement of oxygenated Hb, deoxygnated Hb and total Hb content in rat and human head. After evaluating our method using anesthetized and artificially ventilated rats, this instrument was applied for clinical use, and was useful for the management of clinical patients. The same method was applied to develope the NIR computed tomography (CT). Human X-ray CT was modified for NIR-CT, and CT images were obtained using the back-projection (BP) method. NIR-CT could measure the oxygenation map of the tissues of anesthetized rats.

Citation Download Citation

Ichiro Oda, Yasunobu Ito, Hideo Eda, Tomomi Tamura, Michinosuke Takada, Rentaro Abumi, Katumi Nagai, Hachiro Nakagawa, and Masahide Tamura "Noninvasive hemoglobin oxygenation monitor and computed tomography by NIR spectrophotometry", Proc. SPIE 1431, Time-Resolved Spectroscopy and Imaging of Tissues, (1 May 1991); https://doi.org/10.1117/12.44199

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