Optical Diffractometric Method For Measurement Of Human Red Cells Deformabilitv

Vladislav Blazek; Frantisek Stozicky; Josef Muzik

doi:10.1117/12.959008

15 May 1981 Optical Diffractometric Method For Measurement Of Human Red Cells Deformabilitv

Vladislav Blazek, Frantisek Stozicky, Josef Muzik

Proceedings Volume 0236, 1980 European Conf on Optical Systems and Applications; (1981) https://doi.org/10.1117/12.959008
Event: 1980 European Conference on Optical Systems and Applications, 1980, Utrecht, Netherlands

Abstract

The optical diffractometric method for the measurement of cellular deformability is described. It permits working in real time and enables measuring of an internal viscoelasticity of cells. Deformability of human erythrocytes as a function of applied fluid shear stress is analyzed. It is shown that some limit of proportionality exists below which the deformation of cells is proportional to the fluid shear stress value. But the cells deformability is nearly independent on the stress beyond this limit. Both blood of healthy adults and newborn infants was studied and obtained results are described. Drawbacks of the method are discussed and an improved measuring system is proposed.

Citation Download Citation

Vladislav Blazek, Frantisek Stozicky, and Josef Muzik "Optical Diffractometric Method For Measurement Of Human Red Cells Deformabilitv", Proc. SPIE 0236, 1980 European Conf on Optical Systems and Applications, (15 May 1981); https://doi.org/10.1117/12.959008

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