Localization of spherical photoacoustic sources in acrylamide gels using time domain measurements

John A. Viator; Guenther Paltauf; Steven L. Jacques; Scott A. Prahl

doi:10.1117/12.386309

19 May 2000 Localization of spherical photoacoustic sources in acrylamide gels using time domain measurements

John A. Viator, Guenther Paltauf, Steven L. Jacques, Scott A. Prahl

Proceedings Volume 3916, Biomedical Optoacoustics; (2000) https://doi.org/10.1117/12.386309
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

Photoacoustic imaging may be used to detect tumor masses in biological tissue. In particular, time of flight measurements of the photoacoustic waves may indicate tumor location. Here we use time of flight information to localize spherical photoacoustic sources in tissue phantoms. A Q- switched, frequency-doubled Nd:YAG laser operating at 532nm with a pulse duration of 5 ns irradiated absorbing spheres 2 mm in diameter. The spheres were in mineral oil or turbid acrylamide blocks. A PVDF acoustic transducer was built and used to detect the acoustic waves. The position of the detector was translated so that the time of flight information from two acoustic waveforms from the source could be correlated by a convolution algorithm. This convolution result in a 2D map indicating the position of the source. Source location was indicated to within 5 percent of the true location for acoustic propagation distances of 20 mm. An image source is also indicated when the true source was in proximity to a reflecting boundary.

Citation Download Citation

John A. Viator, Guenther Paltauf, Steven L. Jacques, and Scott A. Prahl "Localization of spherical photoacoustic sources in acrylamide gels using time domain measurements", Proc. SPIE 3916, Biomedical Optoacoustics, (19 May 2000); https://doi.org/10.1117/12.386309

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available