Gene network analysis and design

Matthew J. Berryman; Andrew Allison; Derek Abbott

doi:10.1117/12.582096

16 February 2005 Gene network analysis and design

Matthew J. Berryman, Andrew Allison, Derek Abbott

Proceedings Volume 5651, Biomedical Applications of Micro- and Nanoengineering II; (2005) https://doi.org/10.1117/12.582096
Event: Smart Materials, Nano-, and Micro-Smart Systems, 2004, Sydney, Australia

Abstract

Gene networks are composed of many different interacting genes and gene products (RNAs and proteins). They can be thought of as switching regions in n-dimensional space or as mass-balanced signaling networks. Both approaches allow for describing gene networks with the limited quantitative or even qualitative data available. We show how these approaches can be used in modeling the apoptosis gene network that has a vital role in tumor development. The open question is whether engineering changes to this network could be used as a possible cancer treatment.

Citation Download Citation

Matthew J. Berryman, Andrew Allison, and Derek Abbott "Gene network analysis and design", Proc. SPIE 5651, Biomedical Applications of Micro- and Nanoengineering II, (16 February 2005); https://doi.org/10.1117/12.582096

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