Can normal lymph node architecture be characterised by optical coherence tomography?

R. A. McLaughlin; L. Scolaro; B. R. Klyen; S. Hamza; P. Robbins; C. Saunders; D. D. Sampson

doi:10.1117/12.815182

30 December 2008 Can normal lymph node architecture be characterised by optical coherence tomography?

R. A. McLaughlin, L. Scolaro, B. R. Klyen, S. Hamza, P. Robbins, C. Saunders, D. D. Sampson

Proceedings Volume 7139, 1st Canterbury Workshop on Optical Coherence Tomography and Adaptive Optics; 71390K (2008) https://doi.org/10.1117/12.815182
Event: 1st Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics, 2008, Canterbury, United Kingdom

Abstract

Assessment of lymph node involvement is a key prognostic marker in early breast cancer. This paper demonstrates the ability of optical coherence tomography (OCT) to characterise the micro-architecture of healthy, non-cancerous lymph nodes. OCT is shown to differentiate stroma, cortex and adipose tissue. Characteristic patterns are also identified for germinal centres and blood vessels within the node. Results are correlated against a histopathological gold standard.

Citation Download Citation

R. A. McLaughlin, L. Scolaro, B. R. Klyen, S. Hamza, P. Robbins, C. Saunders, and D. D. Sampson "Can normal lymph node architecture be characterised by optical coherence tomography?", Proc. SPIE 7139, 1st Canterbury Workshop on Optical Coherence Tomography and Adaptive Optics, 71390K (30 December 2008); https://doi.org/10.1117/12.815182

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available