16 February 2010Applications of fluorescence spectroscopy to problems of food safety: detection of fecal contamination and of the presence of central nervous system tissue and diagnosis of neurological disease
Ramkrishna Adhikary, Sayantan Bose, Thomas A. Casey, Al Gapsch, Mark A. Rasmussen, Jacob W. Petrich
Ramkrishna Adhikary,1 Sayantan Bose,1 Thomas A. Casey,2 Al Gapsch,3 Mark A. Rasmussen,4 Jacob W. Petrich1
1Iowa State Univ. (United States) 2National Animal Disease Ctr., USDA (United States) 3TECHnical SOLutions Group, Inc. (United States) 4Ctr. for Veterinary Medicine, U.S. Food and Drug Administration (United States)
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
Applications of fluorescence spectroscopy that enable the real-time or rapid detection of fecal contamination on beef
carcasses and the presence of central nervous system tissue in meat products are discussed. The former is achieved by
employing spectroscopic signatures of chlorophyll metabolites; the latter, by exploiting the characteristic structure and
intensity of lipofuscin in central nervous system tissue. The success of these techniques has led us to investigate the
possibility of diagnosing scrapie in sheep by obtaining fluorescence spectra of the retina. Crucial to this diagnosis is the
ability to obtain baseline correlations of lipofuscin fluorescence with age. A murine model was employed as a proof of
principle of this correlation.
Ramkrishna Adhikary,Sayantan Bose,Thomas A. Casey,Al Gapsch,Mark A. Rasmussen, andJacob W. Petrich
"Applications of fluorescence spectroscopy to problems of food safety: detection of fecal contamination and of the presence of central nervous system tissue and diagnosis of neurological disease", Proc. SPIE 7576, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications II, 757617 (16 February 2010); https://doi.org/10.1117/12.841829
ACCESS THE FULL ARTICLE
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
The alert did not successfully save. Please try again later.
Ramkrishna Adhikary, Sayantan Bose, Thomas A. Casey, Al Gapsch, Mark A. Rasmussen, Jacob W. Petrich, "Applications of fluorescence spectroscopy to problems of food safety: detection of fecal contamination and of the presence of central nervous system tissue and diagnosis of neurological disease," Proc. SPIE 7576, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications II, 757617 (16 February 2010); https://doi.org/10.1117/12.841829