Optoelectronic tweezers for medical diagnostics

Clemens Kremer; Steven Neale; Anoop Menachery; Mike Barrett; Jonathan M. Cooper

doi:10.1117/12.903944

31 January 2012 Optoelectronic tweezers for medical diagnostics

Clemens Kremer, Steven Neale, Anoop Menachery, Mike Barrett, Jonathan M. Cooper

Proceedings Volume 8212, Frontiers in Biological Detection: From Nanosensors to Systems IV; 82120E (2012) https://doi.org/10.1117/12.903944
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

Optoelectronic tweezers (OET) allows the spatial patterning of electric fields through selected illumination of a photoconductive surface. This enables the manipulation of micro particles and cells by creating non-uniform electrical fields that then produce dielectrophoretic (DEP) forces. The DEP responses of cells differ and can produce negative or positive (repelled or attracted to areas of high electric field) forces. Therefore OET can be used to manipulate individual cells and separate different cell types from each other. Thus OET has many applications for medical diagnostics, demonstrated here with work towards diagnosing Human African Trypanosomiasis, also known as sleeping sickness.

Citation Download Citation

Clemens Kremer, Steven Neale, Anoop Menachery, Mike Barrett, and Jonathan M. Cooper "Optoelectronic tweezers for medical diagnostics", Proc. SPIE 8212, Frontiers in Biological Detection: From Nanosensors to Systems IV, 82120E (31 January 2012); https://doi.org/10.1117/12.903944

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