Evaluation of time-resolved multi-distance methods to retrieve absorption and reduced scattering coefficients of adult heads in vivo: Optical parameters dependences on geometrical structures of the models used to calculate reflectance

T. Tanifuji

doi:10.1117/12.2211246

9 March 2016 Evaluation of time-resolved multi-distance methods to retrieve absorption and reduced scattering coefficients of adult heads in vivo: Optical parameters dependences on geometrical structures of the models used to calculate reflectance

T. Tanifuji

Author Affiliations +

Proceedings Volume 9690, Clinical and Translational Neurophotonics; Neural Imaging and Sensing; and Optogenetics and Optical Manipulation; 96900Z (2016) https://doi.org/10.1117/12.2211246
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

Time-resolved multi-distance measurements are studied to retrieve absorption and reduced scattering coefficients of adult heads, which have enough depth sensitivity to determine the optical parameters in superficial tissues and brain separately. Measurements were performed by putting the injection and collection fibers on the left semi-sphere of the forehead, with the injection fiber placed toward the temporal region, and by moving the collection fiber between 10 and 60 mm from the central sulcus. It became clear that optical parameters of the forehead at all collection fibers were reasonably determined by selecting the appropriate visibility length of the geometrical head models, which is related to head surface curvature at each position.

Citation Download Citation

T. Tanifuji "Evaluation of time-resolved multi-distance methods to retrieve absorption and reduced scattering coefficients of adult heads in vivo: Optical parameters dependences on geometrical structures of the models used to calculate reflectance", Proc. SPIE 9690, Clinical and Translational Neurophotonics; Neural Imaging and Sensing; and Optogenetics and Optical Manipulation, 96900Z (9 March 2016); https://doi.org/10.1117/12.2211246

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KEYWORDS

Head

Reflectivity

Sensors

Optical fibers

Absorption

Brain

Scattering

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