24 March 2016 Workflow improvements for digital breast tomosynthesis: computerized generation of enhanced synthetic images
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Abstract
In a typical 2D mammography workflow scenario, a computer-aided detection (CAD) algorithm is used as a second reader producing marks for a radiologist to review. In the case of 3D digital breast tomosynthesis (DBT), the display of CAD detections at multiple reconstruction heights would lead to an increased image browsing and interpretation time. We propose an alternative approach in which an algorithm automatically identifies suspicious regions of interest from 3D reconstructed DBT slices and then merges the findings with the corresponding 2D synthetic projection image which is then reviewed. The resultant enhanced synthetic 2D image combines the benefits of a familiar 2D breast view with superior appearance of suspicious locations from 3D slices. Moreover, clicking on 2D suspicious locations brings up the display of the corresponding 3D regions in a DBT volume allowing navigation between 2D and 3D images. We explored the use of these enhanced synthetic images in a concurrent read paradigm by conducting a study with 5 readers and 30 breast exams. We observed that the introduction of the enhanced synthetic view reduced radiologist's average interpretation time by 5.4%, increased sensitivity by 6.7% and increased specificity by 15.6%.
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Sergei V. Fotin, Yin Yin, Hrishikesh Haldankar, Jeffrey W. Hoffmeister, Senthil Periaswamy, "Workflow improvements for digital breast tomosynthesis: computerized generation of enhanced synthetic images", Proc. SPIE 9785, Medical Imaging 2016: Computer-Aided Diagnosis, 97850K (24 March 2016); doi: 10.1117/12.2217182; https://doi.org/10.1117/12.2217182
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