Towards spatially mapped frequency response of human photoreceptor length variation with flicker optoretinography

Andrea Curatolo; Slawomir Tomczewski; Piotr Wegrzyn; Dawid Borycki; Egidijus Auksorius; Maciej Wojtkowski

doi:10.1117/12.2609513

7 March 2022 Towards spatially mapped frequency response of human photoreceptor length variation with flicker optoretinography

Andrea Curatolo, Slawomir Tomczewski, Piotr Wegrzyn, Dawid Borycki, Egidijus Auksorius, Maciej Wojtkowski

Author Affiliations +

Proceedings Volume PC11941, Ophthalmic Technologies XXXII; PC119410C (2022) https://doi.org/10.1117/12.2609513
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Critical flicker frequency measurements are important in determining the spatial variation of flicker sensitivity in the human retina. An objective and localized measurement of the frequency response of photoreceptors could help elucidate the true physiological mechanisms responsible for such flicker sensitivity variations. Flicker optoretinography (ORG) may be a promising technique for this purpose. In this work, we use Spatio-Temporal Optical Coherence-Tomography to capture flicker optoretinograms to visible patterned light stimulation modulated in the range from few Hz to 30Hz over 5.7º x 2.8º of the retina, at several foveal eccentricities, highlighting the prospect for objective flicker perimetry with ORG.

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Andrea Curatolo, Slawomir Tomczewski, Piotr Wegrzyn, Dawid Borycki, Egidijus Auksorius, and Maciej Wojtkowski "Towards spatially mapped frequency response of human photoreceptor length variation with flicker optoretinography", Proc. SPIE PC11941, Ophthalmic Technologies XXXII, PC119410C (7 March 2022); https://doi.org/10.1117/12.2609513

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