Wide-field human photoreceptor imaging by spatiotemporal optical coherence tomography (STOC-T) in vivo

Dawid Borycki; Egidijus Auksorius; Piotr Wegrzyn; Kamil Lizewski; Slawomir Tomczewski; Ieva Žičkiene; Karolis Adomavičius; Maciej Wojtkowski

doi:10.1117/12.2608837

7 March 2022 Wide-field human photoreceptor imaging by spatiotemporal optical coherence tomography (STOC-T) in vivo

Dawid Borycki, Egidijus Auksorius, Piotr Wegrzyn, Kamil Lizewski, Slawomir Tomczewski, Ieva Žičkiene, Karolis Adomavičius, Maciej Wojtkowski

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Proceedings Volume PC11941, Ophthalmic Technologies XXXII; PC119410I (2022) https://doi.org/10.1117/12.2608837
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Photoreceptors are the primary sensing element of the human visual system. Traditionally, photoreceptors are imaged with hardware-based adaptive optics (AO), which compensate for eye aberrations. However, these systems can be challenging to maintain. Here, we demonstrate the spatiotemporal optical coherence tomography (STOC-T) as the new modality for high-speed, cellular-level volumetric imaging of the human retina in vivo. The cellular features become visible after applying digital aberration corrections. We also show that STOC-T provides cross-sectional images (B-scans) and, concurrently, high-resolution wide-field en face images of the inner and outer human retina layers.

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Dawid Borycki, Egidijus Auksorius, Piotr Wegrzyn, Kamil Lizewski, Slawomir Tomczewski, Ieva Žičkiene, Karolis Adomavičius, and Maciej Wojtkowski "Wide-field human photoreceptor imaging by spatiotemporal optical coherence tomography (STOC-T) in vivo", Proc. SPIE PC11941, Ophthalmic Technologies XXXII, PC119410I (7 March 2022); https://doi.org/10.1117/12.2608837

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KEYWORDS

In vivo imaging

Optical coherence tomography

Adaptive optics

Optical imaging

Retina

Eye

Sensing systems

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