Co-registered optical coherence tomography (OCT) and autofluorescence imaging (AFI) of ex vivo fallopian tubes for early ovarian cancer detection

Jeanie Malone; Geoffrey Hohert; Jessica McAlpine; Lien Hoang; Calum MacAulay; Pierre Lane

doi:10.1117/12.2609994

7 March 2022 Co-registered optical coherence tomography (OCT) and autofluorescence imaging (AFI) of ex vivo fallopian tubes for early ovarian cancer detection

Jeanie Malone, Geoffrey Hohert, Jessica McAlpine, Lien Hoang, Calum MacAulay, Pierre Lane

Author Affiliations +

Proceedings Volume PC11952, Multimodal Biomedical Imaging XVII; PC1195206 (2022) https://doi.org/10.1117/12.2609994
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

The most prevalent ovarian cancers, high-grade serous carcinomas (HGSCs), begin as lesions in the fallopian tubes. There is a need for tools that examine the fallopian tubes for early-stage ovarian cancers. We hypothesize an endoscopic imaging approach combining structural and functional imaging techniques (optical coherence tomography (OCT) and autofluorescence imaging (AFI) respectively) will be able to visualize cancerous or pre-cancerous changes in the fallopian tubes for early ovarian cancer detection. We present findings from an on-going ex vivo imaging study of fallopian tubes including sample cases demonstrating various cancers and preliminary features of interest.

Conference Presentation

Citation Download Citation

Jeanie Malone, Geoffrey Hohert, Jessica McAlpine, Lien Hoang, Calum MacAulay, and Pierre Lane "Co-registered optical coherence tomography (OCT) and autofluorescence imaging (AFI) of ex vivo fallopian tubes for early ovarian cancer detection", Proc. SPIE PC11952, Multimodal Biomedical Imaging XVII, PC1195206 (7 March 2022); https://doi.org/10.1117/12.2609994

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