Presentation
7 March 2022 Non-invasive bedside assessment of microvascular and endothelial health in severe COVID-19 patients: the international HEMOCOVID-19 study
Author Affiliations +
Abstract
The HEMOCOVID-19 clinical trial, carried out in 10 hospitals from 5 countries, aims to non-invasively assess, through continuous-wave near-infrared spectroscopy (CW-NIRS), the microvascular and endothelial health in COVID-19 patients admitted to intensive care. We achieve this by performing a vascular occlusion test on the forearm muscle while continuously measuring local tissue oxygen saturation and hemoglobin concentration. We found significant alterations in systemic microcirculation of COVID-19 patients with respect to healthy subjects (i.e. slower deoxygenation during the ischemia and reoxygenation after releasing the cuff, and lower hyperemic response). In addition, we found that, within the group of COVID-19 patients, the systemic microcirculation alterations correlate with severity of pulmonary disease.
Conference Presentation
© (2022) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
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KEYWORDS
Oxygen

Tissues

Clinical trials

Continuous wave operation

Control systems

Ischemia

Mode conditioning cables

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