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Phantoms were designed to evaluate boundary buildup effect and object detectability. Tissue-mimicking materials simulating breast fat and parenchyma were prepared through emulsification of silicone oil, ethylene glycol and polyacrylamide hydrogel. Imaging targets were prepared by adding either India ink to the water phase or nigrosin to the oil phase. Phantom and inclusion molds were fabricated using an affordable 3D printer, yielding phantoms containing stepped-cylinder inclusions with 1-8 cm-1 optical absorption coefficients and 1-5 mm diameters. Maximum imaging depth depended on whether target boundary buildup or filled-in features were analyzed, with boundary buildup being more detectable.
Jorge Palma-Chavez,Keith A. Wear,Jesse V. Jokerst, andWilliam C. Vogt
"Emulsion-based hydrogel phantoms for assessing boundary buildup and object detectability in photoacoustic imaging", Proc. SPIE PC11960, Photons Plus Ultrasound: Imaging and Sensing 2022, PC119601Y (7 March 2022); https://doi.org/10.1117/12.2609158
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Jorge Palma-Chavez, Keith A. Wear, Jesse V. Jokerst, William C. Vogt, "Emulsion-based hydrogel phantoms for assessing boundary buildup and object detectability in photoacoustic imaging," Proc. SPIE PC11960, Photons Plus Ultrasound: Imaging and Sensing 2022, PC119601Y (7 March 2022); https://doi.org/10.1117/12.2609158