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2 March 2022 Precise localization analysis for high-throughput stimulated Brillouin scattering spectroscopy
Giulia Zanini, Giuliano Scarcelli
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Proceedings Volume PC11962, Optical Elastography and Tissue Biomechanics VIV; PC1196205 (2022) https://doi.org/10.1117/12.2608331
Event: SPIE BiOS, 2022, San Francisco, California, United States
Abstract
Brillouin spectroscopy has emerged as a great modality to non-invasively target mechanical properties in material and biological samples, although it requires high-performance spectrometers and long acquisition times to extract the Brillouin peaks with high SNR and precision. Stimulated Brillouin scattering (SBS) has the potential to improve speed and resolution, achieving a resonant amplification of the scattered signal through the interaction of two counterpropagating laser beams. However, the overall performances of current SBS spectrometers result just comparable to spontaneous Brillouin, and this may indicate that the system is operating with suboptimal acquisition parameters. Here, we will investigate this hypothesis introducing the localization theory in the estimation of the peak position in SBS spectroscopy and demonstrating a ten times improvement in acquisition speed, retaining SNR and precision, by simply designing an SBS spectrometer with proper acquisition parameters.
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Giulia Zanini and Giuliano Scarcelli "Precise localization analysis for high-throughput stimulated Brillouin scattering spectroscopy", Proc. SPIE PC11962, Optical Elastography and Tissue Biomechanics VIV, PC1196205 (2 March 2022); https://doi.org/10.1117/12.2608331
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KEYWORDS
Scattering
Spectroscopy
Biological research
Spectrometers
Acoustics
Laser beam diagnostics
Laser scattering
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