Sensorless adaptive optics multi-modal functional small animal imaging for age-related macular degeneration mouse model

Jun Song; Yusi Miao; Destiny Hsu; Joanne A. Matsubara; Marinko V. Sarunic; Myeong Jin Ju

doi:10.1117/12.2652663

10 March 2023 Sensorless adaptive optics multi-modal functional small animal imaging for age-related macular degeneration mouse model

Jun Song, Yusi Miao, Destiny Hsu, Joanne A. Matsubara, Marinko V. Sarunic, Myeong Jin Ju

Author Affiliations +

Proceedings Volume PC12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII; PC123671G (2023) https://doi.org/10.1117/12.2652663
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

For this study, we developed a multi-modal functional retinal imaging system for small animal models to investigate representative AMD mice models. The system can simultaneously acquire information on melanin concentration, lipofuscin accumulation, and choriocapillaris. The newly developed system is expected to provide multilateral perspectives for further studies in AMD, enabling vision scientists to investigate the correlations between melanin, lipofuscin, and choriocapillaris for the root cause of the disease.

Conference Presentation

Citation Download Citation

Jun Song, Yusi Miao, Destiny Hsu, Joanne A. Matsubara, Marinko V. Sarunic, and Myeong Jin Ju "Sensorless adaptive optics multi-modal functional small animal imaging for age-related macular degeneration mouse model", Proc. SPIE PC12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII, PC123671G (10 March 2023); https://doi.org/10.1117/12.2652663

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