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9 March 2023 A dual-mode photoacoustic and ultrasound imaging system for whole-body small animal studies
Alissa Silva, Edward Zhang, Khoa Pham, Nam Huynh, Michael D. Brown, Olumide Ogunlade, Paul Beard, Ben T. Cox
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Proceedings Volume PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023; PC123790J (2023) https://doi.org/10.1117/12.2656074
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
We present the developments on a simple multiple-view dual-mode photoacoustic/ultrasound system for in-vivo, non-invasive, whole-body small-animal imaging and based on planar Fabry-Pérot sensor-based tomography systems to overcome present challenges. Single planar Fabry-Pérot sensors suffer from an incomplete view of the acoustic fields, which leads to blurring and artefacts in tissue sample images. Increasing the fields of view would relax this limitation. Another contribution to the degradation of the image quality are wavefront aberrations stemming from spatially-varying sound speeds in a tissue sample and which limit the imaging depth. These can however be corrected by carrying out ultrasound computed tomography.
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Alissa Silva, Edward Zhang, Khoa Pham, Nam Huynh, Michael D. Brown, Olumide Ogunlade, Paul Beard, and Ben T. Cox "A dual-mode photoacoustic and ultrasound imaging system for whole-body small animal studies", Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC123790J (9 March 2023); https://doi.org/10.1117/12.2656074
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KEYWORDS
Ultrasonography
Photoacoustic spectroscopy
Imaging systems
Acoustics
Sensors
Absorption
Wavefront aberrations
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