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15 March 2023 Elastographic resolution in the dynamic OCE of bounded nearly incompressible media (Conference Presentation)
Gabriel Regnault, Mitchell A. Kirby, Maju Kuriakose, Ruikang K. Wang, Matthew O'Donnell, Ivan Pelivanov
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Proceedings Volume PC12381, Optical Elastography and Tissue Biomechanics X; PC1238105 (2023) https://doi.org/10.1117/12.2649271
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
Dynamic optical coherence elastography (OCE) tracks mechanical wave propagation in the subsurface region of tissue to map its shear modulus. For bulk shear waves, the lateral resolution of the reconstructed modulus map (i.e., elastographic resolution) can approach that for OCT, typically a few tens of microns. However, skin, cornea and many other tissues are layered or bounded leading to the formation of guided mechanical waves. We performed numerical simulations and acoustic micro-tapping experiments to show that in bounded media, the elastographic resolution cannot reach the OCT structural resolution and is mainly defined by the thickness of the bounded tissue layer.
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Gabriel Regnault, Mitchell A. Kirby, Maju Kuriakose, Ruikang K. Wang, Matthew O'Donnell, and Ivan Pelivanov "Elastographic resolution in the dynamic OCE of bounded nearly incompressible media (Conference Presentation)", Proc. SPIE PC12381, Optical Elastography and Tissue Biomechanics X, PC1238105 (15 March 2023); https://doi.org/10.1117/12.2649271
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KEYWORDS
Elastography
Tissues
Acoustics
Cornea
Optical coherence tomography
Tissue optics
Wave propagation
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