Flexible two-photon lensless endoscope with tapered multicore fibers (Conference Presentation)

Hervé Rigneault; Fatima El Moussawi; Matthias Hofer; Naveen Gajendra Kumar; Damien Labat; Andy Cassez; Geraud Bouwmans; Siddharth Sivankutty; Rosa Cossart; Olivier Vanvincq; Esben Andresen

doi:10.1117/12.2648076

16 March 2023 Flexible two-photon lensless endoscope with tapered multicore fibers (Conference Presentation)

Hervé Rigneault, Fatima El Moussawi, Matthias Hofer, Naveen Gajendra Kumar, Damien Labat, Andy Cassez, Geraud Bouwmans, Siddharth Sivankutty, Rosa Cossart, Olivier Vanvincq, Esben Andresen

Author Affiliations +

Proceedings Volume PC12388, Adaptive Optics and Wavefront Control for Biological Systems IX; PC123880B (2023) https://doi.org/10.1117/12.2648076
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

The lensless endoscope represents the ultimate limit in miniaturization of imaging tools: an image can be transmitted through an optical fiber by numerical or physical inversion of the fiber's pre- measured transmission matrix. We present here a novel fiber-optic component, a "tapered multi-core fiber (MCF)", designed for integration into ultra-miniaturized endoscopes for minimally invasive two-photon point-scanning imaging. This new design addresses the power delivery issue that has faced MCF based lensless endoscopes. We achieve experimentally a factor 6.0 increase in two-photon signal yield while keeping the ability to point-scan by the memory effect. We report two-photon fluorescent imaging of cells and neurons with these improved MCF tapered fibers.

Conference Presentation

Citation Download Citation

Hervé Rigneault, Fatima El Moussawi, Matthias Hofer, Naveen Gajendra Kumar, Damien Labat, Andy Cassez, Geraud Bouwmans, Siddharth Sivankutty, Rosa Cossart, Olivier Vanvincq, and Esben Andresen "Flexible two-photon lensless endoscope with tapered multicore fibers (Conference Presentation)", Proc. SPIE PC12388, Adaptive Optics and Wavefront Control for Biological Systems IX, PC123880B (16 March 2023); https://doi.org/10.1117/12.2648076

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