Evaluation of cell dynamic activity using machine learning and intracellular migration observations (Conference Presentation)

Soongho Park; Thien Nguyen; Vinay Veluvolu; Jinho Park; Amir Gandjbakhche

doi:10.1117/12.2660490

16 March 2023 Evaluation of cell dynamic activity using machine learning and intracellular migration observations (Conference Presentation)

Soongho Park, Thien Nguyen, Vinay Veluvolu, Jinho Park, Amir Gandjbakhche

Author Affiliations +

Proceedings Volume PC12391, Label-free Biomedical Imaging and Sensing (LBIS) 2023; PC1239114 (2023) https://doi.org/10.1117/12.2660490
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

We introduce cell dynamic activity analysis method-based combination of dynamic full-field optical coherence tomography (DFFOCT) and machine learning (ML) models. DFFOCT can monitor intracellular migration label-free by capturing scatters movement inside of cells. Since ML builds classification criteria through learning a lot of data, based on the intracellular scatter migration observed through DFFOCT, it is possible to judge abnormal signs of cells regardless of changes in the external experimental environment. We compared the suggested analysis method and staining analysis method for the change of state of HeLa cells (including cell data) and verified the validity.

Conference Presentation

Citation Download Citation

Soongho Park, Thien Nguyen, Vinay Veluvolu, Jinho Park, and Amir Gandjbakhche "Evaluation of cell dynamic activity using machine learning and intracellular migration observations (Conference Presentation)", Proc. SPIE PC12391, Label-free Biomedical Imaging and Sensing (LBIS) 2023, PC1239114 (16 March 2023); https://doi.org/10.1117/12.2660490

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
PRESENTATION

WATCH
PRESENTATION SAVE TO MY LIBRARY

GET CITATION

KEYWORDS

Machine learning

Diagnostics

Organisms

Imaging systems

Luminescence

Mode conditioning cables

Optical coherence tomography

Show All Keywords

Keywords/Phrases

Search In:

Publication Years