Colorectal cancer (CRC) ranks third globally in terms of prevalence, accounting for 10% of cancer cases and deaths each year. Irreversible electroporation (IRE) offers promise for treating CRC by selectively destroying tumor cells while minimizing harm to healthy tissue. However, the lack of effective guidance and evaluation methods hampers the achievement of complete tumor ablation. To address this, integrated OCT, US, and NIRF endoscopy enable real-time imaging of colorectal tumors, facilitating precise IRE treatment and evaluation of outcomes. In this study, we used an integrated imaging system to precisely guide and evaluate the implementation of IRE therapy in CRC.
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