Evaluation of pulsatile photobiomodulation dosing via nerve cuff

Aaron Skubal; Andrew Buzza; Junqi Zhuo; Michael W. Jenkins; Michael Moffitt

doi:10.1117/12.3002900

13 March 2024 Evaluation of pulsatile photobiomodulation dosing via nerve cuff

Aaron Skubal, Andrew Buzza, Junqi Zhuo, Michael W. Jenkins, Michael Moffitt

Proceedings Volume PC12826, Mechanisms of Photobiomodulation Therapy XVIII; PC1282605 (2024) https://doi.org/10.1117/12.3002900
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Current methods to treat pain have several limitations (e.g., addiction, limited efficacy, etc.) and new options are sorely needed. Photobiomodulation (PBM) at 808 nm has been shown to reduce small fiber axon sensitivities in both human and animal models when applied for the purposes of action potential block. A study using a pulsed light dosing scheme was conducted to determine the viability of using commercially available IPGs for a potential implanted system. Results showed a reduction in pain lasting about 8 days, indicating that this method of delivery has promise for an implanted system.

Conference Presentation

Citation Download Citation

Aaron Skubal, Andrew Buzza, Junqi Zhuo, Michael W. Jenkins, and Michael Moffitt "Evaluation of pulsatile photobiomodulation dosing via nerve cuff", Proc. SPIE PC12826, Mechanisms of Photobiomodulation Therapy XVIII, PC1282605 (13 March 2024); https://doi.org/10.1117/12.3002900

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